BRD-K92093830_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K92093830_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AQP1 aquaporin 1 (Colton blood group)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTG3 BTG family, member 3
CD24 CD24 molecule
CH25H cholesterol 25-hydroxylase
CLCA4 chloride channel accessory 4
CPE carboxypeptidase E
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGFR3 fibroblast growth factor receptor 3
GJA1 gap junction protein, alpha 1, 43kDa
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HBB hemoglobin, beta
HOXD1 homeobox D1
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP7 insulin-like growth factor binding protein 7
IRF6 interferon regulatory factor 6
MUC16 mucin 16, cell surface associated
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PELI1 pellino E3 ubiquitin protein ligase 1
PERP PERP, TP53 apoptosis effector
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
SDC2 syndecan 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFTPA2 surfactant protein A2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
TGFBI transforming growth factor, beta-induced, 68kDa
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CXCL5 chemokine (C-X-C motif) ligand 5
ESR1 estrogen receptor 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATA3 GATA binding protein 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HOXC6 homeobox C6
IER3 immediate early response 3
IGF1R insulin-like growth factor 1 receptor
LTBP3 latent transforming growth factor beta binding protein 3
MSX1 msh homeobox 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPY1R neuropeptide Y receptor Y1
PLA2G16 phospholipase A2, group XVI
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
SORD sorbitol dehydrogenase
SPDEF SAM pointed domain containing ETS transcription factor
TFF1 trefoil factor 1
TRIM37 tripartite motif containing 37
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2