BRD-K92093830_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

167 genes differentially expressed following the BRD-K92093830_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACAA1 acetyl-CoA acyltransferase 1
ACSL5 acyl-CoA synthetase long-chain family member 5
AGA aspartylglucosaminidase
ALCAM activated leukocyte cell adhesion molecule
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA5 annexin A5
APOLD1 apolipoprotein L domain containing 1
ASPN asporin
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C3ORF14 chromosome 3 open reading frame 14
CAPN2 calpain 2, (m/II) large subunit
CAPN3 calpain 3, (p94)
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLIC5 chloride intracellular channel 5
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CSRP2 cysteine and glycine-rich protein 2
CST3 cystatin C
CXCL14 chemokine (C-X-C motif) ligand 14
DACH1 dachshund family transcription factor 1
DCN decorin
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP3 epithelial membrane protein 3
EMX2 empty spiracles homeobox 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERLIN2 ER lipid raft associated 2
GAA glucosidase, alpha; acid
GDE1 glycerophosphodiester phosphodiesterase 1
GOLM1 golgi membrane protein 1
GPM6A glycoprotein M6A
GRN granulin
GSN gelsolin
HIBCH 3-hydroxyisobutyryl-CoA hydrolase
HMGN3 high mobility group nucleosomal binding domain 3
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
INPP1 inositol polyphosphate-1-phosphatase
ISG15 ISG15 ubiquitin-like modifier
ISOC1 isochorismatase domain containing 1
KIAA0226L KIAA0226-like
KIAA1598
LAMP5 lysosomal-associated membrane protein family, member 5
LEF1 lymphoid enhancer-binding factor 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
MLF1 myeloid leukemia factor 1
NEBL nebulette
PBLD phenazine biosynthesis-like protein domain containing
PBX1 pre-B-cell leukemia homeobox 1
PDGFRL platelet-derived growth factor receptor-like
PEA15 phosphoprotein enriched in astrocytes 15
PLAT plasminogen activator, tissue
PLCB4 phospholipase C, beta 4
PLS1 plastin 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PROS1 protein S (alpha)
PTN pleiotrophin
RBKS ribokinase
RBP1 retinol binding protein 1, cellular
RPA3 replication protein A3, 14kDa
RPL37A ribosomal protein L37a
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC35E3 solute carrier family 35, member E3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPON1 spondin 1, extracellular matrix protein
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TP53I3 tumor protein p53 inducible protein 3
TPBG trophoblast glycoprotein
TSPAN13 tetraspanin 13
TSPAN3 tetraspanin 3
TTC39A tetratricopeptide repeat domain 39A
TUBA1A tubulin, alpha 1a
TUBB2B tubulin, beta 2B class IIb
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAN versican
VIM vimentin
WASF3 WAS protein family, member 3
WLS wntless Wnt ligand secretion mediator
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADM adrenomedullin
ADNP activity-dependent neuroprotector homeobox
AHNAK2 AHNAK nucleoprotein 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMD1 adenosylmethionine decarboxylase 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG1 B-cell translocation gene 1, anti-proliferative
C7ORF49 chromosome 7 open reading frame 49
CCNA2 cyclin A2
CDCA4 cell division cycle associated 4
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
CHERP calcium homeostasis endoplasmic reticulum protein
CLCA2 chloride channel accessory 2
CPA3 carboxypeptidase A3 (mast cell)
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
EIF4A1 eukaryotic translation initiation factor 4A1
ERBB3 erb-b2 receptor tyrosine kinase 3
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GRWD1 glutamate-rich WD repeat containing 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGKV1-5 immunoglobulin kappa variable 1-5
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITGA8 integrin, alpha 8
JMJD6 jumonji domain containing 6
KIF2C kinesin family member 2C
KRT7 keratin 7, type II
LRRC41 leucine rich repeat containing 41
LYZ lysozyme
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MET MET proto-oncogene, receptor tyrosine kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NACA nascent polypeptide-associated complex alpha subunit
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NET1 neuroepithelial cell transforming 1
NFIL3 nuclear factor, interleukin 3 regulated
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PAPD7 PAP associated domain containing 7
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RANBP2 RAN binding protein 2
RPL10 ribosomal protein L10
RPL17 ribosomal protein L17
RRP1B ribosomal RNA processing 1B
S100P S100 calcium binding protein P
SEC24B SEC24 family member B
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SIK1 salt-inducible kinase 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TARP TCR gamma alternate reading frame protein
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSKU tsukushi, small leucine rich proteoglycan
WEE1 WEE1 G2 checkpoint kinase
WNT5A wingless-type MMTV integration site family, member 5A