BRD-K91781484_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K91781484_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANXA5 annexin A5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PGD phosphogluconate dehydrogenase
POR P450 (cytochrome) oxidoreductase
RAP1GAP RAP1 GTPase activating protein
RHOB ras homolog family member B
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TKT transketolase
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA4 annexin A4
C7 complement component 7
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCND2 cyclin D2
IL32 interleukin 32
KIAA0753 KIAA0753
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NRIP1 nuclear receptor interacting protein 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS2 regulator of G-protein signaling 2
SEPP1 selenoprotein P, plasma, 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SST somatostatin
VTCN1 V-set domain containing T cell activation inhibitor 1