BRD-K91509126_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-K91509126_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CD58 CD58 molecule
GCLM glutamate-cysteine ligase, modifier subunit
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAT2A methionine adenosyltransferase II, alpha
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PGD phosphogluconate dehydrogenase
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
CKB creatine kinase, brain
EIF5B eukaryotic translation initiation factor 5B
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HECA headcase homolog (Drosophila)
LTBP3 latent transforming growth factor beta binding protein 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
ZEB1 zinc finger E-box binding homeobox 1