BRD-K91349888_arg-a1-22 BRD-K91349888_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K91349888_arg-a1-22 BRD-K91349888_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AIM2 absent in melanoma 2
AKR1C1 aldo-keto reductase family 1, member C1
ANPEP alanyl (membrane) aminopeptidase
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BAG3 BCL2-associated athanogene 3
C1ORF116 chromosome 1 open reading frame 116
CAPN2 calpain 2, (m/II) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CD93 CD93 molecule
COLEC12 collectin sub-family member 12
CPM carboxypeptidase M
CRABP1 cellular retinoic acid binding protein 1
CST3 cystatin C
CTSH cathepsin H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FABP4 fatty acid binding protein 4, adipocyte
FAM46A family with sequence similarity 46, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GPR183 G protein-coupled receptor 183
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
LAMP3 lysosomal-associated membrane protein 3
LGALS3 lectin, galactoside-binding, soluble, 3
LPL lipoprotein lipase
MAOA monoamine oxidase A
MARCO macrophage receptor with collagenous structure
MATN2 matrilin 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1E metallothionein 1E
MT1M metallothionein 1M
NR4A1 nuclear receptor subfamily 4, group A, member 1
NT5E 5'-nucleotidase, ecto (CD73)
PDGFC platelet derived growth factor C
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARG peroxisome proliferator-activated receptor gamma
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDC4 syndecan 4
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SST somatostatin
THBD thrombomodulin

decreased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
CALD1 caldesmon 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
F2R coagulation factor II (thrombin) receptor
GAS1 growth arrest-specific 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
IFITM1 interferon induced transmembrane protein 1
KDM5D lysine (K)-specific demethylase 5D
KIF14 kinesin family member 14
LIPG lipase, endothelial
MAN1A1 mannosidase, alpha, class 1A, member 1
NRN1 neuritin 1
NUP210 nucleoporin 210kDa
PCCB propionyl CoA carboxylase, beta polypeptide
PDE4B phosphodiesterase 4B, cAMP-specific
PIP prolactin-induced protein
PROM1 prominin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCGB2A2 secretoglobin, family 2A, member 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TTC3 tetratricopeptide repeat domain 3