BRD-K91349888_arg-a1-22 BRD-K91349888_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

231 genes differentially expressed following the BRD-K91349888_arg-a1-22 BRD-K91349888_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AEBP1 AE binding protein 1
ANGPT2 angiopoietin 2
ARMCX1 armadillo repeat containing, X-linked 1
ASPN asporin
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BAX BCL2-associated X protein
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BGN biglycan
BPHL biphenyl hydrolase-like (serine hydrolase)
BTG2 BTG family, member 2
C3ORF14 chromosome 3 open reading frame 14
CADM1 cell adhesion molecule 1
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CD24 CD24 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKB creatine kinase, brain
CLCA1 chloride channel accessory 1
COL3A1 collagen, type III, alpha 1
COL8A2 collagen, type VIII, alpha 2
COL9A1 collagen, type IX, alpha 1
CORO1A coronin, actin binding protein, 1A
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
DCN decorin
DENND1B DENN/MADD domain containing 1B
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
ESR1 estrogen receptor 1
EVI2A ecotropic viral integration site 2A
FRZB frizzled-related protein
FZD10 frizzled class receptor 10
GFAP glial fibrillary acidic protein
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPM6B glycoprotein M6B
GREB1 growth regulation by estrogen in breast cancer 1
GUSBP11 glucuronidase, beta pseudogene 11
HIST1H2BG histone cluster 1, H2bg
HIST2H2BE histone cluster 2, H2be
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INHBA inhibin, beta A
ISOC1 isochorismatase domain containing 1
ISYNA1 inositol-3-phosphate synthase 1
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
LYPD1 LY6/PLAUR domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MEIS2 Meis homeobox 2
MT1F metallothionein 1F
MT1X metallothionein 1X
MUC16 mucin 16, cell surface associated
MZB1 marginal zone B and B1 cell-specific protein
NCAM1 neural cell adhesion molecule 1
NEB nebulin
NEBL nebulette
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRCAM neuronal cell adhesion molecule
OGN osteoglycin
PAK1IP1 PAK1 interacting protein 1
PAWR PRKC, apoptosis, WT1, regulator
PCP4 Purkinje cell protein 4
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKCI protein kinase C, iota
PRKX protein kinase, X-linked
PTN pleiotrophin
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP1 retinol binding protein 1, cellular
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
RGS16 regulator of G-protein signaling 16
RGS5 regulator of G-protein signaling 5
SCG5 secretogranin V
SDC1 syndecan 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP4 secreted frizzled-related protein 4
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC38A1 solute carrier family 38, member 1
SOX17 SRY (sex determining region Y)-box 17
SPARCL1 SPARC-like 1 (hevin)
SPON2 spondin 2, extracellular matrix protein
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SST somatostatin
STC1 stanniocalcin 1
STON1 stonin 1
SULF1 sulfatase 1
TCEAL2 transcription elongation factor A (SII)-like 2
TCF4 transcription factor 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB3 transforming growth factor, beta 3
TOX thymocyte selection-associated high mobility group box
TSPAN7 tetraspanin 7
TUBB2B tubulin, beta 2B class IIb
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)
ZC2HC1A zinc finger, C2HC-type containing 1A
ZIC1 Zic family member 1
ZNF232 zinc finger protein 232
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMD1 adenosylmethionine decarboxylase 1
ANXA6 annexin A6
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASPH aspartate beta-hydroxylase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCLAF1 BCL2-associated transcription factor 1
BLVRA biliverdin reductase A
BMI1 BMI1 proto-oncogene, polycomb ring finger
BST2 bone marrow stromal cell antigen 2
C8ORF4 chromosome 8 open reading frame 4
CALD1 caldesmon 1
CBR3 carbonyl reductase 3
CCL19 chemokine (C-C motif) ligand 19
CCR7 chemokine (C-C motif) receptor 7
CD36 CD36 molecule (thrombospondin receptor)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHPT1 choline phosphotransferase 1
CHSY1 chondroitin sulfate synthase 1
CST3 cystatin C
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH1 cytohesin 1
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DENND5A DENN/MADD domain containing 5A
DNM1 dynamin 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ERBB2 erb-b2 receptor tyrosine kinase 2
FERMT2 fermitin family member 2
FGF13 fibroblast growth factor 13
FOLR1 folate receptor 1 (adult)
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GOLGA8A golgin A8 family, member A
GPATCH8 G patch domain containing 8
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HOXA10 homeobox A10
HOXA5 homeobox A5
HOXC6 homeobox C6
IL6ST interleukin 6 signal transducer
KDM5D lysine (K)-specific demethylase 5D
KIAA0125 KIAA0125
KIF20A kinesin family member 20A
KRT10 keratin 10, type I
LAMP1 lysosomal-associated membrane protein 1
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LOX lysyl oxidase
LTBP3 latent transforming growth factor beta binding protein 3
LY75 lymphocyte antigen 75
MAPK6 mitogen-activated protein kinase 6
MSL1 male-specific lethal 1 homolog (Drosophila)
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNT nicotinamide nucleotide transhydrogenase
NPC2 Niemann-Pick disease, type C2
NPY neuropeptide Y
NRGN neurogranin (protein kinase C substrate, RC3)
NRN1 neuritin 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PFKL phosphofructokinase, liver
PGD phosphogluconate dehydrogenase
PHF20 PHD finger protein 20
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PMP22 peripheral myelin protein 22
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRC1 protein regulator of cytokinesis 1
PROM1 prominin 1
PTX3 pentraxin 3, long
QDPR quinoid dihydropteridine reductase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPL36 ribosomal protein L36
RPS4Y1 ribosomal protein S4, Y-linked 1
SACS sacsin molecular chaperone
SCML1 sex comb on midleg-like 1 (Drosophila)
SFRP1 secreted frizzled-related protein 1
SIDT2 SID1 transmembrane family, member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNX11 sorting nexin 11
SORBS3 sorbin and SH3 domain containing 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPP1 secreted phosphoprotein 1
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TMED3 transmembrane emp24 protein transport domain containing 3
TMEM47 transmembrane protein 47
TNC tenascin C
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRIM16 tripartite motif containing 16
TSPAN3 tetraspanin 3
TSPAN8 tetraspanin 8
UBE2E1 ubiquitin-conjugating enzyme E2E 1
VCL vinculin
ZBTB18 zinc finger and BTB domain containing 18
ZNF185 zinc finger protein 185 (LIM domain)