BRD-K91263825_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K91263825_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
FADS1 fatty acid desaturase 1
FASN fatty acid synthase
FDPS farnesyl diphosphate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KDM5D lysine (K)-specific demethylase 5D
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
POR P450 (cytochrome) oxidoreductase
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
SQSTM1 sequestosome 1
VIM vimentin

decreased expression

Symbol Name
ASCL1 achaete-scute family bHLH transcription factor 1
COTL1 coactosin-like F-actin binding protein 1
CPE carboxypeptidase E
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EDNRA endothelin receptor type A
IGHM immunoglobulin heavy constant mu
PALLD palladin, cytoskeletal associated protein
PLS3 plastin 3
RGS2 regulator of G-protein signaling 2
SNX7 sorting nexin 7
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
XIST X inactive specific transcript (non-protein coding)