BRD-K90826279_-666_SW620_6.0_h_20.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K90826279_-666_SW620_6.0_h_20.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
BHLHE41 basic helix-loop-helix family, member e41
CALD1 caldesmon 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAPN2 calpain 2, (m/II) large subunit
CD44 CD44 molecule (Indian blood group)
CFD complement factor D (adipsin)
CPB1 carboxypeptidase B1 (tissue)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DLD dihydrolipoamide dehydrogenase
DST dystonin
EFHD1 EF-hand domain family, member D1
EGFR epidermal growth factor receptor
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBB hemoglobin, beta
HIC2 hypermethylated in cancer 2
IGL immunoglobulin lambda locus
IGLL1 immunoglobulin lambda-like polypeptide 1
KRT6B keratin 6B, type II
MAN1A1 mannosidase, alpha, class 1A, member 1
NCK2 NCK adaptor protein 2
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID2 nidogen 2 (osteonidogen)
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PSD3 pleckstrin and Sec7 domain containing 3
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RB1CC1 RB1-inducible coiled-coil 1
S100A13 S100 calcium binding protein A13
S100A14 S100 calcium binding protein A14
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SFRP1 secreted frizzled-related protein 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPG20 spastic paraplegia 20 (Troyer syndrome)
TBX3 T-box 3
TFPI2 tissue factor pathway inhibitor 2
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
UFM1 ubiquitin-fold modifier 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XPO7 exportin 7
YPEL5 yippee-like 5 (Drosophila)
ZEB2 zinc finger E-box binding homeobox 2

decreased expression

Symbol Name
BASP1 brain abundant, membrane attached signal protein 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CES1 carboxylesterase 1
CLEC2B C-type lectin domain family 2, member B
COL9A3 collagen, type IX, alpha 3
CPVL carboxypeptidase, vitellogenic-like
CTSH cathepsin H
FABP7 fatty acid binding protein 7, brain
FKBP5 FK506 binding protein 5
GADD45B growth arrest and DNA-damage-inducible, beta
GPC3 glypican 3
GPX3 glutathione peroxidase 3
HIST1H2BG histone cluster 1, H2bg
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL1R2 interleukin 1 receptor, type II
LOC100505650 uncharacterized LOC100505650
LPL lipoprotein lipase
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLK1 polo-like kinase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPATS2L spermatogenesis associated, serine-rich 2-like
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TIMP3 TIMP metallopeptidase inhibitor 3
TMED3 transmembrane emp24 protein transport domain containing 3
U2AF1 U2 small nuclear RNA auxiliary factor 1
ZIC1 Zic family member 1