BRD-K90524085_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K90524085_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARG2 arginase 2
BLNK B-cell linker
BTG3 BTG family, member 3
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CHRDL1 chordin-like 1
CLIC2 chloride intracellular channel 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CRYM crystallin, mu
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DKK3 dickkopf WNT signaling pathway inhibitor 3
DOCK4 dedicator of cytokinesis 4
EXT1 exostosin glycosyltransferase 1
FAM129A family with sequence similarity 129, member A
FRZB frizzled-related protein
FTH1 ferritin, heavy polypeptide 1
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
GSTP1 glutathione S-transferase pi 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
LGALS1 lectin, galactoside-binding, soluble, 1
LITAF lipopolysaccharide-induced TNF factor
MDFIC MyoD family inhibitor domain containing
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MX1 MX dynamin-like GTPase 1
NANOG Nanog homeobox
NPTX2 neuronal pentraxin II
NXN nucleoredoxin
PCLO piccolo presynaptic cytomatrix protein
PDE2A phosphodiesterase 2A, cGMP-stimulated
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
QPCT glutaminyl-peptide cyclotransferase
RPL10 ribosomal protein L10
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC1 syndecan 1
SDC2 syndecan 2
SHB Src homology 2 domain containing adaptor protein B
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TFPI2 tissue factor pathway inhibitor 2
TRIB3 tribbles pseudokinase 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
CD99 CD99 molecule
CLTC clathrin, heavy chain (Hc)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CST3 cystatin C
DHCR7 7-dehydrocholesterol reductase
EFNB2 ephrin-B2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FAM46A family with sequence similarity 46, member A
FDPS farnesyl diphosphate synthase
FOLR1 folate receptor 1 (adult)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FZD7 frizzled class receptor 7
GCH1 GTP cyclohydrolase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXB7 homeobox B7
INSIG1 insulin induced gene 1
KCTD12 potassium channel tetramerization domain containing 12
LAMC1 laminin, gamma 1 (formerly LAMB2)
LDLR low density lipoprotein receptor
MAGEA12 melanoma antigen family A12
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
MSRB2 methionine sulfoxide reductase B2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NOTCH3 notch 3
NREP neuronal regeneration related protein
NRN1 neuritin 1
PI3 peptidase inhibitor 3, skin-derived
REEP1 receptor accessory protein 1
S100P S100 calcium binding protein P
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SQLE squalene epoxidase