BRD-K90446118_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K90446118_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCL3 B-cell CLL/lymphoma 3
C1S complement component 1, s subcomponent
C3 complement component 3
CAPG capping protein (actin filament), gelsolin-like
CCL19 chemokine (C-C motif) ligand 19
CH25H cholesterol 25-hydroxylase
CLU clusterin
COL4A2 collagen, type IV, alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBLN1 fibulin 1
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
LMO4 LIM domain only 4
PPAP2B phosphatidic acid phosphatase type 2B
RHOB ras homolog family member B
SEPP1 selenoprotein P, plasma, 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2

decreased expression

Symbol Name
CCNE2 cyclin E2
CDCA4 cell division cycle associated 4
COL10A1 collagen, type X, alpha 1
CPE carboxypeptidase E
H2AFV H2A histone family, member V
MSLN mesothelin
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PDE10A phosphodiesterase 10A
ZBTB18 zinc finger and BTB domain containing 18