BRD-K90382497_GW-843682X_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K90382497_GW-843682X_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CDH19 cadherin 19, type 2
CLC Charcot-Leyden crystal galectin
CRABP2 cellular retinoic acid binding protein 2
CYR61 cysteine-rich, angiogenic inducer, 61
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GBP2 guanylate binding protein 2, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
GPM6B glycoprotein M6B
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HIST1H2AC histone cluster 1, H2ac
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOXB7 homeobox B7
IGFBP5 insulin-like growth factor binding protein 5
MYOF myoferlin
PHLDA1 pleckstrin homology-like domain, family A, member 1
RBM34 RNA binding motif protein 34
SDC2 syndecan 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SSFA2 sperm specific antigen 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM47 transmembrane protein 47
UGDH UDP-glucose 6-dehydrogenase
USP6NL USP6 N-terminal like
XIST X inactive specific transcript (non-protein coding)
ZFP36L1 ZFP36 ring finger protein-like 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRB2 adrenoceptor beta 2, surface
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ASRGL1 asparaginase like 1
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
CCNF cyclin F
CDK1 cyclin-dependent kinase 1
CES1 carboxylesterase 1
CKS2 CDC28 protein kinase regulatory subunit 2
CLEC2B C-type lectin domain family 2, member B
CRIP1 cysteine-rich protein 1 (intestinal)
CYBA cytochrome b-245, alpha polypeptide
DNM1L dynamin 1-like
E2F2 E2F transcription factor 2
EGFL6 EGF-like-domain, multiple 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMX2 empty spiracles homeobox 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM60A family with sequence similarity 60, member A
HMGB3 high mobility group box 3
IFITM1 interferon induced transmembrane protein 1
KAZN kazrin, periplakin interacting protein
KCTD12 potassium channel tetramerization domain containing 12
LAMP5 lysosomal-associated membrane protein family, member 5
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MMP12 matrix metallopeptidase 12
NPY neuropeptide Y
NREP neuronal regeneration related protein
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
SATB1 SATB homeobox 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMYD2 SET and MYND domain containing 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SRGN serglycin
STAT1 signal transducer and activator of transcription 1, 91kDa
WFDC2 WAP four-disulfide core domain 2