BRD-K90027355_spironolactone_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

28 genes differentially expressed following the BRD-K90027355_spironolactone_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CEP57 centrosomal protein 57kDa
EPB41L3 erythrocyte membrane protein band 4.1-like 3
KRT13 keratin 13, type I
KRT15 keratin 15, type I
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MTSS1 metastasis suppressor 1
NEB nebulin
NPTX2 neuronal pentraxin II
PDE4B phosphodiesterase 4B, cAMP-specific
PSCA prostate stem cell antigen
RCAN2 regulator of calcineurin 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SPON2 spondin 2, extracellular matrix protein
WFDC1 WAP four-disulfide core domain 1

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
F12 coagulation factor XII (Hageman factor)
GNAS GNAS complex locus
HOXC6 homeobox C6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
PRR7 proline rich 7 (synaptic)
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
VAT1 vesicle amine transport 1