BRD-K89997465_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K89997465_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
BAG3 BCL2-associated athanogene 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD81 CD81 molecule
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
EPCAM epithelial cell adhesion molecule
FBN2 fibrillin 2
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GDF15 growth differentiation factor 15
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LAMP5 lysosomal-associated membrane protein family, member 5
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
MYO6 myosin VI
NPC2 Niemann-Pick disease, type C2
NSDHL NAD(P) dependent steroid dehydrogenase-like
PLA2G16 phospholipase A2, group XVI
RBPMS RNA binding protein with multiple splicing
RRBP1 ribosome binding protein 1
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SQLE squalene epoxidase
SQSTM1 sequestosome 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
VGLL4 vestigial-like family member 4

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
COL3A1 collagen, type III, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CRABP1 cellular retinoic acid binding protein 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EIF5A eukaryotic translation initiation factor 5A
FABP1 fatty acid binding protein 1, liver
FRZB frizzled-related protein
GBP1 guanylate binding protein 1, interferon-inducible
HBB hemoglobin, beta
MMP12 matrix metallopeptidase 12
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
SULF1 sulfatase 1