BRD-K89853519_FISETINIDOL_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K89853519_FISETINIDOL_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
BASP1 brain abundant, membrane attached signal protein 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
DHRS7 dehydrogenase/reductase (SDR family) member 7
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DST dystonin
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
MBNL1 muscleblind-like splicing regulator 1
MIR22HG MIR22 host gene
NEFH neurofilament, heavy polypeptide
PENK proenkephalin
PHLDA2 pleckstrin homology-like domain, family A, member 2
PSAP prosaposin
PTGDS prostaglandin D2 synthase 21kDa (brain)
RCAN1 regulator of calcineurin 1
SERP1 stress-associated endoplasmic reticulum protein 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRAM1 translocation associated membrane protein 1
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CPE carboxypeptidase E
GPNMB glycoprotein (transmembrane) nmb
IGHM immunoglobulin heavy constant mu
POU2AF1 POU class 2 associating factor 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SPINK1 serine peptidase inhibitor, Kazal type 1
ZNF395 zinc finger protein 395