BRD-K89692698_-666_SW620_6.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K89692698_-666_SW620_6.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
ARG2 arginase 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BPTF bromodomain PHD finger transcription factor
C6ORF62 chromosome 6 open reading frame 62
CCNG2 cyclin G2
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CLGN calmegin
CLU clusterin
COBL cordon-bleu WH2 repeat protein
DDIT4 DNA-damage-inducible transcript 4
DOK5 docking protein 5
DSG2 desmoglein 2
DUSP2 dual specificity phosphatase 2
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERBB3 erb-b2 receptor tyrosine kinase 3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GDF15 growth differentiation factor 15
GREM1 gremlin 1, DAN family BMP antagonist
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KLHL24 kelch-like family member 24
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT7 keratin 7, type II
KRT8 keratin 8, type II
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MSMB microseminoprotein, beta-
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PDE4B phosphodiesterase 4B, cAMP-specific
PPAP2C phosphatidic acid phosphatase type 2C
PRNP prion protein
PRUNE2 prune homolog 2 (Drosophila)
PTN pleiotrophin
RAB40B RAB40B, member RAS oncogene family
RAI14 retinoic acid induced 14
RGCC regulator of cell cycle
S100A13 S100 calcium binding protein A13
SCN3A sodium channel, voltage gated, type III alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SGK1 serum/glucocorticoid regulated kinase 1
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SYT1 synaptotagmin I
TCTA T-cell leukemia translocation altered
TMSB15A thymosin beta 15a
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPR translocated promoter region, nuclear basket protein
TRIB3 tribbles pseudokinase 3
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZNF12 zinc finger protein 12

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BAX BCL2-associated X protein
BST2 bone marrow stromal cell antigen 2
CDCA4 cell division cycle associated 4
COL2A1 collagen, type II, alpha 1
CTSZ cathepsin Z
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
DAPK1 death-associated protein kinase 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
FBLN1 fibulin 1
FBN2 fibrillin 2
FKBP10 FK506 binding protein 10, 65 kDa
FLRT2 fibronectin leucine rich transmembrane protein 2
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GRWD1 glutamate-rich WD repeat containing 1
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP6 insulin-like growth factor binding protein 6
IL1R2 interleukin 1 receptor, type II
LAMP1 lysosomal-associated membrane protein 1
MAOA monoamine oxidase A
MSL1 male-specific lethal 1 homolog (Drosophila)
PLAC8 placenta-specific 8
PLTP phospholipid transfer protein
PTMA prothymosin, alpha
REG1A regenerating islet-derived 1 alpha
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
TSPAN3 tetraspanin 3
TSPAN4 tetraspanin 4