BRD-K89005359_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K89005359_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BMP4 bone morphogenetic protein 4
CD40 CD40 molecule, TNF receptor superfamily member 5
COL4A6 collagen, type IV, alpha 6
CPE carboxypeptidase E
CTBP2 C-terminal binding protein 2
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DOCK4 dedicator of cytokinesis 4
EIF1 eukaryotic translation initiation factor 1
FGFR2 fibroblast growth factor receptor 2
GJA1 gap junction protein, alpha 1, 43kDa
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGL immunoglobulin lambda locus
IL13RA1 interleukin 13 receptor, alpha 1
IPO13 importin 13
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
LCK LCK proto-oncogene, Src family tyrosine kinase
LIMCH1 LIM and calponin homology domains 1
PIP prolactin-induced protein
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POU2AF1 POU class 2 associating factor 1
PSD3 pleckstrin and Sec7 domain containing 3
QPCT glutaminyl-peptide cyclotransferase
RGCC regulator of cell cycle
SERINC5 serine incorporator 5
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SH3BGRL SH3 domain binding glutamate-rich protein like

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ARG1 arginase 1
C6ORF62 chromosome 6 open reading frame 62
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CHL1 cell adhesion molecule L1-like
DAPK1 death-associated protein kinase 1
DEFB1 defensin, beta 1
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
FAM46A family with sequence similarity 46, member A
G0S2 G0/G1 switch 2
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
PLTP phospholipid transfer protein
RBP4 retinol binding protein 4, plasma
RPA3 replication protein A3, 14kDa
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UGCG UDP-glucose ceramide glucosyltransferase
ZIC1 Zic family member 1