BRD-K88868628_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K88868628_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ATF3 activating transcription factor 3
CD36 CD36 molecule (thrombospondin receptor)
CD9 CD9 molecule
CES1 carboxylesterase 1
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A2 collagen, type I, alpha 2
CYBB cytochrome b-245, beta polypeptide
DLK1 delta-like 1 homolog (Drosophila)
EMP1 epithelial membrane protein 1
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
GAL galanin/GMAP prepropeptide
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HYOU1 hypoxia up-regulated 1
IGFBP5 insulin-like growth factor binding protein 5
KRT19 keratin 19, type I
KYNU kynureninase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MB myoglobin
NOVA1 neuro-oncological ventral antigen 1
PEG10 paternally expressed 10
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SNN stannin
TMEM45A transmembrane protein 45A
TNNT1 troponin T type 1 (skeletal, slow)
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAPZB capping protein (actin filament) muscle Z-line, beta
CD320 CD320 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAT1 FAT atypical cadherin 1
HSPA2 heat shock 70kDa protein 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MCOLN1 mucolipin 1
NFIB nuclear factor I/B
PCDH9 protocadherin 9
PEBP1 phosphatidylethanolamine binding protein 1
RGS2 regulator of G-protein signaling 2
SPTBN1 spectrin, beta, non-erythrocytic 1
TM4SF1 transmembrane 4 L six family member 1
TXNIP thioredoxin interacting protein
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)