BRD-K88573743_A443654_MDAMB231_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K88573743_A443654_MDAMB231_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARHGAP29 Rho GTPase activating protein 29
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CCL20 chemokine (C-C motif) ligand 20
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CNPY3 canopy FGF signaling regulator 3
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DKK1 dickkopf WNT signaling pathway inhibitor 1
EREG epiregulin
GADD45B growth arrest and DNA-damage-inducible, beta
GAL galanin/GMAP prepropeptide
GATA3 GATA binding protein 3
HHEX hematopoietically expressed homeobox
HIST1H2BD histone cluster 1, H2bd
HOPX HOP homeobox
KIAA0355 KIAA0355
KLK5 kallikrein-related peptidase 5
MTERF3 mitochondrial transcription termination factor 3
MXRA5 matrix-remodelling associated 5
MYO1B myosin IB
NUP85 nucleoporin 85kDa
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PELI1 pellino E3 ubiquitin protein ligase 1
PODXL podocalyxin-like
PON3 paraoxonase 3
RGS5 regulator of G-protein signaling 5
SAMD4A sterile alpha motif domain containing 4A
SPARCL1 SPARC-like 1 (hevin)

decreased expression

Symbol Name
AGR2 anterior gradient 2
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CD52 CD52 molecule
CD69 CD69 molecule
CIRBP cold inducible RNA binding protein
COL1A2 collagen, type I, alpha 2
COL6A3 collagen, type VI, alpha 3
CTSK cathepsin K
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
ERAP2 endoplasmic reticulum aminopeptidase 2
ETV1 ets variant 1
FXYD3 FXYD domain containing ion transport regulator 3
GDF15 growth differentiation factor 15
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HNMT histamine N-methyltransferase
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
LAMA4 laminin, alpha 4
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGED1 melanoma antigen family D1
MANSC1 MANSC domain containing 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK13 mitogen-activated protein kinase 13
MMP1 matrix metallopeptidase 1
NPTX2 neuronal pentraxin II
PHKB phosphorylase kinase, beta
QSOX1 quiescin Q6 sulfhydryl oxidase 1
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC16A4 solute carrier family 16, member 4
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPON1 spondin 1, extracellular matrix protein
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
SRPX sushi-repeat containing protein, X-linked
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TOX3 TOX high mobility group box family member 3
TPSAB1 tryptase alpha/beta 1
TRIM22 tripartite motif containing 22
VCAM1 vascular cell adhesion molecule 1
WWTR1 WW domain containing transcription regulator 1
YBX3 Y box binding protein 3