BRD-K88573743_A443654_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K88573743_A443654_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKRD10 ankyrin repeat domain 10
BHLHE40 basic helix-loop-helix family, member e40
CAPN6 calpain 6
DSP desmoplakin
FCGBP Fc fragment of IgG binding protein
GPX3 glutathione peroxidase 3
HAPLN1 hyaluronan and proteoglycan link protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL1R2 interleukin 1 receptor, type II
KAZN kazrin, periplakin interacting protein
KIAA0907 KIAA0907
KLHL21 kelch-like family member 21
KRT14 keratin 14, type I
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
NSG1 neuron specific gene family member 1
OAT ornithine aminotransferase
PNMAL1 paraneoplastic Ma antigen family-like 1
PTHLH parathyroid hormone-like hormone
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SORBS3 sorbin and SH3 domain containing 3
THBS4 thrombospondin 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPBG trophoblast glycoprotein
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TXNIP thioredoxin interacting protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VTCN1 V-set domain containing T cell activation inhibitor 1
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ATF3 activating transcription factor 3
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CAST calpastatin
CCNE2 cyclin E2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
GDF15 growth differentiation factor 15
GRB7 growth factor receptor-bound protein 7
GTPBP8 GTP-binding protein 8 (putative)
KAT6B K(lysine) acetyltransferase 6B
KYNU kynureninase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEF2C myocyte enhancer factor 2C
NEBL nebulette
NNMT nicotinamide N-methyltransferase
NR2F1 nuclear receptor subfamily 2, group F, member 1
PECR peroxisomal trans-2-enoyl-CoA reductase
RGCC regulator of cell cycle
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SNAP25 synaptosomal-associated protein, 25kDa
TBP TATA box binding protein
TMEM176B transmembrane protein 176B
TMSB15A thymosin beta 15a
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1