BRD-K88573743_A443654_MCF10A_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K88573743_A443654_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASPN asporin
BAX BCL2-associated X protein
BST2 bone marrow stromal cell antigen 2
C10ORF10 chromosome 10 open reading frame 10
CD24 CD24 molecule
CDC42 cell division cycle 42
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLIC3 chloride intracellular channel 3
CUTA cutA divalent cation tolerance homolog (E. coli)
CYBA cytochrome b-245, alpha polypeptide
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FHL1 four and a half LIM domains 1
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GJA1 gap junction protein, alpha 1, 43kDa
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HOPX HOP homeobox
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOX lysyl oxidase
MFAP5 microfibrillar associated protein 5
MMP1 matrix metallopeptidase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PDE8B phosphodiesterase 8B
PEG10 paternally expressed 10
PLN phospholamban
PPAP2B phosphatidic acid phosphatase type 2B
PYCARD PYD and CARD domain containing
REEP5 receptor accessory protein 5
RGS5 regulator of G-protein signaling 5
SNAP25 synaptosomal-associated protein, 25kDa
TFF1 trefoil factor 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZIC1 Zic family member 1

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
AQP1 aquaporin 1 (Colton blood group)
AREG amphiregulin
CYR61 cysteine-rich, angiogenic inducer, 61
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EED embryonic ectoderm development
EGR1 early growth response 1
EIF5 eukaryotic translation initiation factor 5
ERBB2 erb-b2 receptor tyrosine kinase 2
EZR ezrin
FAS Fas cell surface death receptor
FGF13 fibroblast growth factor 13
FOS FBJ murine osteosarcoma viral oncogene homolog
HSPA2 heat shock 70kDa protein 2
IGHM immunoglobulin heavy constant mu
KLF4 Kruppel-like factor 4 (gut)
KRT23 keratin 23, type I
KRT5 keratin 5, type II
MME membrane metallo-endopeptidase
MYO10 myosin X
NCF2 neutrophil cytosolic factor 2
OXTR oxytocin receptor
PELI1 pellino E3 ubiquitin protein ligase 1
RGS2 regulator of G-protein signaling 2
S100A11 S100 calcium binding protein A11
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TBP TATA box binding protein
TLE4 transducin-like enhancer of split 4
VCAN versican