BRD-K88573743_A443654_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K88573743_A443654_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA2 actin, alpha 2, smooth muscle, aorta
ADIRF adipogenesis regulatory factor
AGR2 anterior gradient 2
ANO1 anoctamin 1, calcium activated chloride channel
C7 complement component 7
CFD complement factor D (adipsin)
COL6A3 collagen, type VI, alpha 3
CSRP2 cysteine and glycine-rich protein 2
CYFIP2 cytoplasmic FMR1 interacting protein 2
DENND2D DENN/MADD domain containing 2D
DKK3 dickkopf WNT signaling pathway inhibitor 3
DST dystonin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ETV1 ets variant 1
FAM171A1 family with sequence similarity 171, member A1
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
FOXF1 forkhead box F1
GSTP1 glutathione S-transferase pi 1
IGFBP5 insulin-like growth factor binding protein 5
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTA4H leukotriene A4 hydrolase
LTBP1 latent transforming growth factor beta binding protein 1
MAB21L2 mab-21-like 2 (C. elegans)
MT1E metallothionein 1E
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
PLAT plasminogen activator, tissue
QDPR quinoid dihydropteridine reductase
RBP1 retinol binding protein 1, cellular
SCG5 secretogranin V
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SPINK1 serine peptidase inhibitor, Kazal type 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TBX2 T-box 2
TFF1 trefoil factor 1
TMBIM6 transmembrane BAX inhibitor motif containing 6

decreased expression

Symbol Name
ANXA1 annexin A1
ASF1A anti-silencing function 1A histone chaperone
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDCA4 cell division cycle associated 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2AIP CDKN2A interacting protein
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHD7 chromodomain helicase DNA binding protein 7
CHIC2 cysteine-rich hydrophobic domain 2
CKLF chemokine-like factor
CREB1 cAMP responsive element binding protein 1
CTGF connective tissue growth factor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSP desmoplakin
DUSP5 dual specificity phosphatase 5
EIF5 eukaryotic translation initiation factor 5
FLG filaggrin
GATA2 GATA binding protein 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HHEX hematopoietically expressed homeobox
HIST1H4C histone cluster 1, H4c
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KCTD5 potassium channel tetramerization domain containing 5
KLF11 Kruppel-like factor 11
KLF4 Kruppel-like factor 4 (gut)
KRT23 keratin 23, type I
KRT6B keratin 6B, type II
MAT2A methionine adenosyltransferase II, alpha
NET1 neuroepithelial cell transforming 1
NFIL3 nuclear factor, interleukin 3 regulated
NRIP1 nuclear receptor interacting protein 1
PELO pelota homolog (Drosophila)
PERP PERP, TP53 apoptosis effector
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RAE1 ribonucleic acid export 1
RND3 Rho family GTPase 3
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCAF8 SR-related CTD-associated factor 8
SCYL3 SCY1-like 3 (S. cerevisiae)
SIK1 salt-inducible kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SULF1 sulfatase 1
TBP TATA box binding protein
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TXNIP thioredoxin interacting protein