BRD-K88573743_A443654_LNCAP_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K88573743_A443654_LNCAP_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
APOD apolipoprotein D
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLC Charcot-Leyden crystal galectin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GSTM3 glutathione S-transferase mu 3 (brain)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL17RB interleukin 17 receptor B
IL2RG interleukin 2 receptor, gamma
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0907 KIAA0907
LRP4 low density lipoprotein receptor-related protein 4
LUM lumican
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN2B1 mannosidase, alpha, class 2B, member 1
MBNL2 muscleblind-like splicing regulator 2
MGP matrix Gla protein
MSMB microseminoprotein, beta-
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
MYBPC1 myosin binding protein C, slow type
NEFL neurofilament, light polypeptide
NES nestin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB4 phospholipase C, beta 4
POSTN periostin, osteoblast specific factor
PPAP2B phosphatidic acid phosphatase type 2B
RSRP1 arginine/serine-rich protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLIT2 slit homolog 2 (Drosophila)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TNC tenascin C
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)

decreased expression

Symbol Name
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
CD69 CD69 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
HACD3 3-hydroxyacyl-CoA dehydratase 3
KLK10 kallikrein-related peptidase 10
LCN2 lipocalin 2
MAT2A methionine adenosyltransferase II, alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RBM15B RNA binding motif protein 15B
SCYL3 SCY1-like 3 (S. cerevisiae)
TBP TATA box binding protein
TFPI2 tissue factor pathway inhibitor 2
TRIB3 tribbles pseudokinase 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WFDC2 WAP four-disulfide core domain 2
WSB1 WD repeat and SOCS box containing 1