BRD-K88573743_A443654_LNCAP_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

88 genes differentially expressed following the BRD-K88573743_A443654_LNCAP_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
BASP1 brain abundant, membrane attached signal protein 1
CD9 CD9 molecule
COL8A2 collagen, type VIII, alpha 2
GATA2 GATA binding protein 2
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GRN granulin
GSPT2 G1 to S phase transition 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IRS2 insulin receptor substrate 2
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
MERTK MER proto-oncogene, tyrosine kinase
METTL7A methyltransferase like 7A
MMP9 matrix metallopeptidase 9
MT1M metallothionein 1M
MTCL1 microtubule crosslinking factor 1
NAV2 neuron navigator 2
NEFL neurofilament, light polypeptide
NPC1 Niemann-Pick disease, type C1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PLAT plasminogen activator, tissue
PNMA2 paraneoplastic Ma antigen 2
PPAP2B phosphatidic acid phosphatase type 2B
PRKCH protein kinase C, eta
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS5 regulator of G-protein signaling 5
RPL31 ribosomal protein L31
RSRP1 arginine/serine-rich protein 1
SESN1 sestrin 1
SLC35E2B solute carrier family 35, member E2B
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPATA20 spermatogenesis associated 20
SRSF7 serine/arginine-rich splicing factor 7
TUSC3 tumor suppressor candidate 3
WDR45 WD repeat domain 45
ZMIZ1 zinc finger, MIZ-type containing 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
APOB apolipoprotein B
ATF5 activating transcription factor 5
BCL2 B-cell CLL/lymphoma 2
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLIC4 chloride intracellular channel 4
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CXCL12 chemokine (C-X-C motif) ligand 12
DEFB1 defensin, beta 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
ENO1 enolase 1, (alpha)
ETV1 ets variant 1
FN1 fibronectin 1
GALE UDP-galactose-4-epimerase
GINS2 GINS complex subunit 2 (Psf2 homolog)
HEBP2 heme binding protein 2
HN1 hematological and neurological expressed 1
IGFBP5 insulin-like growth factor binding protein 5
IGKV1-5 immunoglobulin kappa variable 1-5
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
LAPTM4B lysosomal protein transmembrane 4 beta
MAPK9 mitogen-activated protein kinase 9
MOCOS molybdenum cofactor sulfurase
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NQO1 NAD(P)H dehydrogenase, quinone 1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PECR peroxisomal trans-2-enoyl-CoA reductase
PERP PERP, TP53 apoptosis effector
PLK1 polo-like kinase 1
PROM1 prominin 1
PSAT1 phosphoserine aminotransferase 1
REEP5 receptor accessory protein 5
RFC2 replication factor C (activator 1) 2, 40kDa
RPL38 ribosomal protein L38
RRM2 ribonucleotide reductase M2
RTN4 reticulon 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SNX10 sorting nexin 10
THBS1 thrombospondin 1
TMEM47 transmembrane protein 47
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
WDR1 WD repeat domain 1