BRD-K88573743_A443654_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K88573743_A443654_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ANKRD10 ankyrin repeat domain 10
APLP2 amyloid beta (A4) precursor-like protein 2
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CES1 carboxylesterase 1
CFI complement factor I
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CPVL carboxypeptidase, vitellogenic-like
CSTA cystatin A (stefin A)
CTSH cathepsin H
DPYSL3 dihydropyrimidinase-like 3
DSP desmoplakin
DUOX2 dual oxidase 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ERLIN2 ER lipid raft associated 2
GAS1 growth arrest-specific 1
GBP2 guanylate binding protein 2, interferon-inducible
HNMT histamine N-methyltransferase
HOXA5 homeobox A5
HOXC6 homeobox C6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL1R1 interleukin 1 receptor, type I
KRT5 keratin 5, type II
LYZ lysozyme
MDFIC MyoD family inhibitor domain containing
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP7 matrix metallopeptidase 7
MSRA methionine sulfoxide reductase A
MT1F metallothionein 1F
MT1M metallothionein 1M
NPC2 Niemann-Pick disease, type C2
PDLIM3 PDZ and LIM domain 3
PID1 phosphotyrosine interaction domain containing 1
PRNP prion protein
RGS5 regulator of G-protein signaling 5
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SFN stratifin
SSPN sarcospan
STEAP1 six transmembrane epithelial antigen of the prostate 1
STS steroid sulfatase (microsomal), isozyme S
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZBTB18 zinc finger and BTB domain containing 18
ZCCHC14 zinc finger, CCHC domain containing 14

decreased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ANXA3 annexin A3
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
COL9A3 collagen, type IX, alpha 3
EIF5 eukaryotic translation initiation factor 5
GPM6B glycoprotein M6B
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAL mal, T-cell differentiation protein
MBP myelin basic protein
MID1IP1 MID1 interacting protein 1
NEBL nebulette
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PICALM phosphatidylinositol binding clathrin assembly protein
RAD51C RAD51 paralog C
RFTN1 raftlin, lipid raft linker 1
TBP TATA box binding protein