BRD-K88573743_A443654_HS578T_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K88573743_A443654_HS578T_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADIRF adipogenesis regulatory factor
ASRGL1 asparaginase like 1
CD8A CD8a molecule
CDC25B cell division cycle 25B
CHRDL1 chordin-like 1
CRABP1 cellular retinoic acid binding protein 1
DUSP6 dual specificity phosphatase 6
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
F13A1 coagulation factor XIII, A1 polypeptide
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR3 fibroblast growth factor receptor 3
GSTA1 glutathione S-transferase alpha 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMK granzyme K (granzyme 3; tryptase II)
H3F3B H3 histone, family 3B (H3.3B)
HDAC6 histone deacetylase 6
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
IDO1 indoleamine 2,3-dioxygenase 1
IGF1R insulin-like growth factor 1 receptor
JUN jun proto-oncogene
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIAA0355 KIAA0355
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MYO5C myosin VC
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEK2 pleckstrin 2
PROM1 prominin 1
PRSS3 protease, serine, 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STX1A syntaxin 1A (brain)
TSTA3 tissue specific transplantation antigen P35B
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ATF5 activating transcription factor 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BMP7 bone morphogenetic protein 7
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CCL2 chemokine (C-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DERA deoxyribose-phosphate aldolase (putative)
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
FABP7 fatty acid binding protein 7, brain
FDX1 ferredoxin 1
FLRT3 fibronectin leucine rich transmembrane protein 3
GSTT1 glutathione S-transferase theta 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HMOX1 heme oxygenase 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
LAPTM4B lysosomal protein transmembrane 4 beta
LMO4 LIM domain only 4
LOXL1 lysyl oxidase-like 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NEFH neurofilament, heavy polypeptide
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR2F6 nuclear receptor subfamily 2, group F, member 6
NREP neuronal regeneration related protein
NSDHL NAD(P) dependent steroid dehydrogenase-like
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCCB propionyl CoA carboxylase, beta polypeptide
PCP4 Purkinje cell protein 4
PDGFA platelet-derived growth factor alpha polypeptide
PGC progastricsin (pepsinogen C)
PON2 paraoxonase 2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
QPRT quinolinate phosphoribosyltransferase
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD23B RAD23 homolog B (S. cerevisiae)
SC5D sterol-C5-desaturase
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SNAP25 synaptosomal-associated protein, 25kDa
SOAT1 sterol O-acyltransferase 1
SPP1 secreted phosphoprotein 1
TBX2 T-box 2
TM7SF2 transmembrane 7 superfamily member 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
WNT5A wingless-type MMTV integration site family, member 5A
YAP1 Yes-associated protein 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1