BRD-K88573743_A443654_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K88573743_A443654_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADIRF adipogenesis regulatory factor
ALB albumin
ARID5B AT rich interactive domain 5B (MRF1-like)
ASPN asporin
CD9 CD9 molecule
CHIC2 cysteine-rich hydrophobic domain 2
FGFR2 fibroblast growth factor receptor 2
GATA3 GATA binding protein 3
GLUD2 glutamate dehydrogenase 2
GREM1 gremlin 1, DAN family BMP antagonist
GSN gelsolin
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LAMP1 lysosomal-associated membrane protein 1
LOX lysyl oxidase
MFAP5 microfibrillar associated protein 5
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC38A1 solute carrier family 38, member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TES testin LIM domain protein
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TKTL1 transketolase-like 1
TWIST1 twist family bHLH transcription factor 1
VEGFA vascular endothelial growth factor A
ZEB1 zinc finger E-box binding homeobox 1

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
CD24 CD24 molecule
CRYAB crystallin, alpha B
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
EGFR epidermal growth factor receptor
EGR1 early growth response 1
HMGN3 high mobility group nucleosomal binding domain 3
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
KPNB1 karyopherin (importin) beta 1
MET MET proto-oncogene, receptor tyrosine kinase
NCK1 NCK adaptor protein 1
NEFL neurofilament, light polypeptide
NRN1 neuritin 1
PLA2G16 phospholipase A2, group XVI
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFN stratifin
SSBP1 single-stranded DNA binding protein 1, mitochondrial
TBP TATA box binding protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSPAN8 tetraspanin 8
TUBA4A tubulin, alpha 4a