BRD-K88556033_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K88556033_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
C10ORF10 chromosome 10 open reading frame 10
CA2 carbonic anhydrase II
CD40 CD40 molecule, TNF receptor superfamily member 5
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPE carboxypeptidase E
GAGE3 G antigen 3
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRTN3 proteinase 3
RGCC regulator of cell cycle

decreased expression

Symbol Name
ASPA aspartoacylase
ATF5 activating transcription factor 5
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BASP1 brain abundant, membrane attached signal protein 1
GOLGA8A golgin A8 family, member A
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
KIAA0485 uncharacterized LOC57235
LAPTM4B lysosomal protein transmembrane 4 beta
MAP7 microtubule-associated protein 7
MBP myelin basic protein
MEIS1 Meis homeobox 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
RGS2 regulator of G-protein signaling 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SOSTDC1 sclerostin domain containing 1