BRD-K88510285_B675700.cdx_SW480_6.0_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-K88510285_B675700.cdx_SW480_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALB albumin
APP amyloid beta (A4) precursor protein
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
CCNA1 cyclin A1
CD200 CD200 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
EIF5 eukaryotic translation initiation factor 5
ELOVL5 ELOVL fatty acid elongase 5
EXT1 exostosin glycosyltransferase 1
FBXO21 F-box protein 21
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBB hemoglobin, beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI16 interferon, gamma-inducible protein 16
INSIG1 insulin induced gene 1
L1CAM L1 cell adhesion molecule
LCN2 lipocalin 2
LOC100505650 uncharacterized LOC100505650
MICU2 mitochondrial calcium uptake 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP7 matrix metallopeptidase 7
MSMO1 methylsterol monooxygenase 1
NNMT nicotinamide N-methyltransferase
OLFM4 olfactomedin 4
PDZK1IP1 PDZK1 interacting protein 1
PLAC8 placenta-specific 8
PROM1 prominin 1
PXDN peroxidasin
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RND3 Rho family GTPase 3
S100A8 S100 calcium binding protein A8
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCPEP1 serine carboxypeptidase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
TLK2 tousled-like kinase 2
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
TUSC3 tumor suppressor candidate 3
VTCN1 V-set domain containing T cell activation inhibitor 1
ZCCHC8 zinc finger, CCHC domain containing 8
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AKAP12 A kinase (PRKA) anchor protein 12
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
B3GNT1
BSG basigin (Ok blood group)
CAST calpastatin
CCND2 cyclin D2
CD59 CD59 molecule, complement regulatory protein
CFD complement factor D (adipsin)
CRIP1 cysteine-rich protein 1 (intestinal)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCR4 chemokine (C-X-C motif) receptor 4
DHFR dihydrofolate reductase
DMD dystrophin
FCGBP Fc fragment of IgG binding protein
FKBP2 FK506 binding protein 2, 13kDa
GPM6A glycoprotein M6A
KRT20 keratin 20, type I
MAGEA3 melanoma antigen family A3
MFAP5 microfibrillar associated protein 5
MGP matrix Gla protein
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NFIB nuclear factor I/B
PBX3 pre-B-cell leukemia homeobox 3
PCNA proliferating cell nuclear antigen
PEBP1 phosphatidylethanolamine binding protein 1
PLSCR3 phospholipid scramblase 3
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBPMS RNA binding protein with multiple splicing
RPL37A ribosomal protein L37a
SDC4 syndecan 4
SEPT8 septin 8
SLC35F2 solute carrier family 35, member F2
TSPAN4 tetraspanin 4
TUBB6 tubulin, beta 6 class V
TYMS thymidylate synthetase
UBE2S ubiquitin-conjugating enzyme E2S
VAT1 vesicle amine transport 1