BRD-K88510285_B675700.cdx_RMUGS_6.0_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

125 genes differentially expressed following the BRD-K88510285_B675700.cdx_RMUGS_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CD163 CD163 molecule
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLDN10 claudin 10
CLIC4 chloride intracellular channel 4
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSE dermatan sulfate epimerase
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
F3 coagulation factor III (thromboplastin, tissue factor)
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GCLM glutamate-cysteine ligase, modifier subunit
GDF15 growth differentiation factor 15
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
HP haptoglobin
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
IFRD1 interferon-related developmental regulator 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
JUNB jun B proto-oncogene
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP7 microtubule-associated protein 7
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MOB4 MOB family member 4, phocein
MSX1 msh homeobox 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
NQO1 NAD(P)H dehydrogenase, quinone 1
PLIN2 perilipin 2
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRDX2 peroxiredoxin 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RNF114 ring finger protein 114
RSL1D1 ribosomal L1 domain containing 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SH3YL1 SH3 and SYLF domain containing 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNX13 sorting nexin 13
SPAG9 sperm associated antigen 9
SQSTM1 sequestosome 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPD52L1 tumor protein D52-like 1
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
AK4 adenylate kinase 4
BCHE butyrylcholinesterase
C14ORF132 chromosome 14 open reading frame 132
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAV1 caveolin 1, caveolae protein, 22kDa
CCL5 chemokine (C-C motif) ligand 5
CELF2 CUGBP, Elav-like family member 2
CORO1A coronin, actin binding protein, 1A
CRIP2 cysteine-rich protein 2
CSRP1 cysteine and glycine-rich protein 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
EFS embryonal Fyn-associated substrate
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
FBLN1 fibulin 1
FGF9 fibroblast growth factor 9
GAS1 growth arrest-specific 1
HMGA2 high mobility group AT-hook 2
HNMT histamine N-methyltransferase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFNAR1 interferon (alpha, beta and omega) receptor 1
INA internexin neuronal intermediate filament protein, alpha
INHBB inhibin, beta B
JAG1 jagged 1
NES nestin
NVL nuclear VCP-like
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG3 paternally expressed 3
PIP prolactin-induced protein
S100A7 S100 calcium binding protein A7
SH3BGRL SH3 domain binding glutamate-rich protein like
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
SYNM synemin, intermediate filament protein
TGFBR3 transforming growth factor, beta receptor III
TMPRSS3 transmembrane protease, serine 3
TNS1 tensin 1
TNS3 tensin 3
TOX3 TOX high mobility group box family member 3
TRIL TLR4 interactor with leucine-rich repeats
WFDC1 WAP four-disulfide core domain 1