BRD-K88510285_B675700.cdx_PL21_6.0_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

148 genes differentially expressed following the BRD-K88510285_B675700.cdx_PL21_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ADGRG1 adhesion G protein-coupled receptor G1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
C3ORF14 chromosome 3 open reading frame 14
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
COL6A1 collagen, type VI, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CSRP1 cysteine and glycine-rich protein 1
CSRP2 cysteine and glycine-rich protein 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
FGFR3 fibroblast growth factor receptor 3
FXR1 fragile X mental retardation, autosomal homolog 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GPX2 glutathione peroxidase 2
GSN gelsolin
GSTP1 glutathione S-transferase pi 1
GUSBP11 glucuronidase, beta pseudogene 11
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
KRT18 keratin 18, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LEFTY1 left-right determination factor 1
MAOB monoamine oxidase B
MFSD10 major facilitator superfamily domain containing 10
MMP7 matrix metallopeptidase 7
MYBPC1 myosin binding protein C, slow type
OLFM4 olfactomedin 4
PEG10 paternally expressed 10
PIR pirin (iron-binding nuclear protein)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAD9A RAD9 homolog A (S. pombe)
RGCC regulator of cell cycle
S100P S100 calcium binding protein P
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SFRP4 secreted frizzled-related protein 4
SLAMF7 SLAM family member 7
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINK1 serine peptidase inhibitor, Kazal type 1
SQSTM1 sequestosome 1
SYNM synemin, intermediate filament protein
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TPD52 tumor protein D52
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UFD1L ubiquitin fusion degradation 1 like (yeast)
XBP1 X-box binding protein 1
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
APOC1 apolipoprotein C-I
BIK BCL2-interacting killer (apoptosis-inducing)
C14ORF159 chromosome 14 open reading frame 159
CCNG1 cyclin G1
CD36 CD36 molecule (thrombospondin receptor)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSTA cystatin A (stefin A)
CTSC cathepsin C
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
FRY furry homolog (Drosophila)
FXYD5 FXYD domain containing ion transport regulator 5
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GRB14 growth factor receptor-bound protein 14
GTF3A general transcription factor IIIA
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IFI44L interferon-induced protein 44-like
IFRD2 interferon-related developmental regulator 2
LOX lysyl oxidase
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
METTL7A methyltransferase like 7A
MSRB2 methionine sulfoxide reductase B2
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NR2F2 nuclear receptor subfamily 2, group F, member 2
OSBPL10 oxysterol binding protein-like 10
PCCB propionyl CoA carboxylase, beta polypeptide
PDLIM2 PDZ and LIM domain 2 (mystique)
PLA2G15 phospholipase A2, group XV
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
QDPR quinoid dihydropteridine reductase
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS13 regulator of G-protein signaling 13
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMAD6 SMAD family member 6
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNIK TRAF2 and NCK interacting kinase
TRIM14 tripartite motif containing 14
TRIM22 tripartite motif containing 22
VAT1 vesicle amine transport 1
ZNF586 zinc finger protein 586
ZNF91 zinc finger protein 91