BRD-K88510285_B675700.cdx_HEC108_6.0_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K88510285_B675700.cdx_HEC108_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
AKR1C1 aldo-keto reductase family 1, member C1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLIC4 chloride intracellular channel 4
CLU clusterin
CNOT4 CCR4-NOT transcription complex, subunit 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
F3 coagulation factor III (thromboplastin, tissue factor)
FHL2 four and a half LIM domains 2
FRMD4B FERM domain containing 4B
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IFRD1 interferon-related developmental regulator 1
LIMS1 LIM and senescent cell antigen-like domains 1
MAP7 microtubule-associated protein 7
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
ODC1 ornithine decarboxylase 1
RAE1 ribonucleic acid export 1
REEP1 receptor accessory protein 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLPI secretory leukocyte peptidase inhibitor
SNX11 sorting nexin 11
SYNE2 spectrin repeat containing, nuclear envelope 2
TM4SF1 transmembrane 4 L six family member 1
TXNRD1 thioredoxin reductase 1
UBE3C ubiquitin protein ligase E3C
XBP1 X-box binding protein 1

decreased expression

Symbol Name
CCND1 cyclin D1
CIAPIN1 cytokine induced apoptosis inhibitor 1
DEGS1 delta(4)-desaturase, sphingolipid 1
EMP3 epithelial membrane protein 3
FGFR3 fibroblast growth factor receptor 3
HOXA10 homeobox A10
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
IGFBP3 insulin-like growth factor binding protein 3
IL27RA interleukin 27 receptor, alpha
LGALS1 lectin, galactoside-binding, soluble, 1
LY6E lymphocyte antigen 6 complex, locus E
MARCKSL1 MARCKS-like 1
MDFIC MyoD family inhibitor domain containing
PLK2 polo-like kinase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC2 syndecan 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPON2 spondin 2, extracellular matrix protein
TRIB2 tribbles pseudokinase 2
TYRP1 tyrosinase-related protein 1
VCAN versican