BRD-K88510285_B675700.cdx_HCT116_6.0_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

210 genes differentially expressed following the BRD-K88510285_B675700.cdx_HCT116_6.0_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BLNK B-cell linker
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BTG3 BTG family, member 3
C6ORF48 chromosome 6 open reading frame 48
CANX calnexin
CARS cysteinyl-tRNA synthetase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CHMP1B charged multivesicular body protein 1B
CLIC4 chloride intracellular channel 4
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
CTH cystathionine gamma-lyase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DSE dermatan sulfate epimerase
DSP desmoplakin
EAPP E2F-associated phosphoprotein
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5 eukaryotic translation initiation factor 5
EMX2 empty spiracles homeobox 2
EPRS glutamyl-prolyl-tRNA synthetase
FN1 fibronectin 1
FTH1 ferritin, heavy polypeptide 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GARS glycyl-tRNA synthetase
GCLM glutamate-cysteine ligase, modifier subunit
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IARS isoleucyl-tRNA synthetase
IFRD1 interferon-related developmental regulator 1
IGKV4-1 immunoglobulin kappa variable 4-1
INPP5F inositol polyphosphate-5-phosphatase F
IQCG IQ motif containing G
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KRT6A keratin 6A, type II
LOX lysyl oxidase
MAN2A1 mannosidase, alpha, class 2A, member 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARS methionyl-tRNA synthetase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP12 matrix metallopeptidase 12
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIL3 nuclear factor, interleukin 3 regulated
NPC1 Niemann-Pick disease, type C1
NUPR1 nuclear protein, transcriptional regulator, 1
OSER1 oxidative stress responsive serine-rich 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PEG3 paternally expressed 3
PHGDH phosphoglycerate dehydrogenase
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RABGGTB Rab geranylgeranyltransferase, beta subunit
RANBP9 RAN binding protein 9
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RIOK3 RIO kinase 3
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCFD1 sec1 family domain containing 1
SEC31A SEC31 homolog A (S. cerevisiae)
SEC63 SEC63 homolog (S. cerevisiae)
SEPT2 septin 2
SERP1 stress-associated endoplasmic reticulum protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3YL1 SH3 and SYLF domain containing 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TARS threonyl-tRNA synthetase
TF transferrin
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TRIM22 tripartite motif containing 22
UBE2A ubiquitin-conjugating enzyme E2A
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
USP1 ubiquitin specific peptidase 1
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
XBP1 X-box binding protein 1
YARS tyrosyl-tRNA synthetase
ZDHHC6 zinc finger, DHHC-type containing 6

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADGRE5 adhesion G protein-coupled receptor E5
ADIRF adipogenesis regulatory factor
APOD apolipoprotein D
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
BCL2L1 BCL2-like 1
BIRC5 baculoviral IAP repeat containing 5
CANT1 calcium activated nucleotidase 1
CCND1 cyclin D1
CCND3 cyclin D3
CCNF cyclin F
CDC25B cell division cycle 25B
CHRDL1 chordin-like 1
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPNE1 copine I
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYBA cytochrome b-245, alpha polypeptide
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DOK4 docking protein 4
FHL1 four and a half LIM domains 1
FTO fat mass and obesity associated
GALE UDP-galactose-4-epimerase
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GSPT2 G1 to S phase transition 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H4C histone cluster 1, H4c
HN1 hematological and neurological expressed 1
HOXA10 homeobox A10
HOXC10 homeobox C10
HOXC6 homeobox C6
IFITM1 interferon induced transmembrane protein 1
IGFBP7 insulin-like growth factor binding protein 7
ISG15 ISG15 ubiquitin-like modifier
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM4B lysine (K)-specific demethylase 4B
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LY6E lymphocyte antigen 6 complex, locus E
MAGEA3 melanoma antigen family A3
METRN meteorin, glial cell differentiation regulator
MGLL monoglyceride lipase
MMD monocyte to macrophage differentiation-associated
MRPL12 mitochondrial ribosomal protein L12
MTSS1 metastasis suppressor 1
MVP major vault protein
MXRA7 matrix-remodelling associated 7
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRN1 neuritin 1
NTS neurotensin
OSBPL10 oxysterol binding protein-like 10
PEG10 paternally expressed 10
PLK1 polo-like kinase 1
PNMA2 paraneoplastic Ma antigen 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRR7 proline rich 7 (synaptic)
S100A4 S100 calcium binding protein A4
SCAND1 SCAN domain containing 1
SEPT9 septin 9
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SOX9 SRY (sex determining region Y)-box 9
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
THSD7A thrombospondin, type I, domain containing 7A
TNC tenascin C
TNS1 tensin 1
TSPAN4 tetraspanin 4
TUBA1A tubulin, alpha 1a
ZFP36L2 ZFP36 ring finger protein-like 2