BRD-K88378636_withaferin-a_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K88378636_withaferin-a_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL9A3 collagen, type IX, alpha 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
EGR3 early growth response 3
EPCAM epithelial cell adhesion molecule
ETV5 ets variant 5
FCGBP Fc fragment of IgG binding protein
FTH1 ferritin, heavy polypeptide 1
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER2 immediate early response 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
JUN jun proto-oncogene
PDPN podoplanin
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
PLSCR3 phospholipid scramblase 3
PON3 paraoxonase 3
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCG5 secretogranin V
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SRPX sushi-repeat containing protein, X-linked
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
BTBD3 BTB (POZ) domain containing 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CST1 cystatin SN
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EREG epiregulin
FERMT1 fermitin family member 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HP haptoglobin
IL1RN interleukin 1 receptor antagonist
KDM5D lysine (K)-specific demethylase 5D
KRT13 keratin 13, type I
KRT17 keratin 17, type I
KRT23 keratin 23, type I
KRT6A keratin 6A, type II
MSMO1 methylsterol monooxygenase 1
MYH11 myosin, heavy chain 11, smooth muscle
PI3 peptidase inhibitor 3, skin-derived
PLAGL1 pleiomorphic adenoma gene-like 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SOX4 SRY (sex determining region Y)-box 4
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR3 small proline-rich protein 3
SYT1 synaptotagmin I
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
TSPAN1 tetraspanin 1