BRD-K88172511_naltrexone_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K88172511_naltrexone_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATM ATM serine/threonine kinase
EREG epiregulin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSL2 FOS-like antigen 2
KRT17 keratin 17, type I
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PON2 paraoxonase 2

decreased expression

Symbol Name
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
DCN decorin
FST follistatin
GNAS GNAS complex locus
INSIG1 insulin induced gene 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3