BRD-K87947369_VX-680_MDST8_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

128 genes differentially expressed following the BRD-K87947369_VX-680_MDST8_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGAP6 Rho GTPase activating protein 6
ASS1 argininosuccinate synthase 1
AURKA aurora kinase A
CDC20 cell division cycle 20
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHEK2 checkpoint kinase 2
COL1A1 collagen, type I, alpha 1
CRISP3 cysteine-rich secretory protein 3
CYBA cytochrome b-245, alpha polypeptide
EBP emopamil binding protein (sterol isomerase)
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FADS1 fatty acid desaturase 1
GABPB1 GA binding protein transcription factor, beta subunit 1
GPRC5B G protein-coupled receptor, class C, group 5, member B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
IGFBP4 insulin-like growth factor binding protein 4
KIF20A kinesin family member 20A
KRT13 keratin 13, type I
KRT19 keratin 19, type I
LXN latexin
MATN2 matrilin 2
MBNL2 muscleblind-like splicing regulator 2
MEIS2 Meis homeobox 2
MPPED2 metallophosphoesterase domain containing 2
NDN necdin, melanoma antigen (MAGE) family member
NEB nebulin
NPIPB3 nuclear pore complex interacting protein family, member B3
NQO1 NAD(P)H dehydrogenase, quinone 1
NTS neurotensin
OSR2 odd-skipped related transciption factor 2
PITX1 paired-like homeodomain 1
PNISR PNN-interacting serine/arginine-rich protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS1 tensin 1
TNS3 tensin 3
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
UBQLN2 ubiquilin 2
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AREG amphiregulin
BIRC2 baculoviral IAP repeat containing 2
CA2 carbonic anhydrase II
CAV1 caveolin 1, caveolae protein, 22kDa
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CISH cytokine inducible SH2-containing protein
CKAP4 cytoskeleton-associated protein 4
CNIH3 cornichon family AMPA receptor auxiliary protein 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGFR epidermal growth factor receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EREG epiregulin
EXT1 exostosin glycosyltransferase 1
FAM134B family with sequence similarity 134, member B
FOSL1 FOS-like antigen 1
FST follistatin
FZD1 frizzled class receptor 1
GEM GTP binding protein overexpressed in skeletal muscle
GLS glutaminase
GPNMB glycoprotein (transmembrane) nmb
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HBEGF heparin-binding EGF-like growth factor
HK2 hexokinase 2
HMGA2 high mobility group AT-hook 2
HPCAL1 hippocalcin-like 1
IFI27 interferon, alpha-inducible protein 27
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IL13RA2 interleukin 13 receptor, alpha 2
IL1B interleukin 1, beta
INHBA inhibin, beta A
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA6 integrin, alpha 6
JUN jun proto-oncogene
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT6B keratin 6B, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAP1B microtubule-associated protein 1B
MGLL monoglyceride lipase
MREG melanoregulin
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PAPD7 PAP associated domain containing 7
PDGFA platelet-derived growth factor alpha polypeptide
PLAT plasminogen activator, tissue
PTHLH parathyroid hormone-like hormone
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RCAN1 regulator of calcineurin 1
RNF167 ring finger protein 167
SDC1 syndecan 1
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC38A1 solute carrier family 38, member 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTSSA serine palmitoyltransferase, small subunit A
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TFB2M transcription factor B2, mitochondrial
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNIP1 TNFAIP3 interacting protein 1
YAP1 Yes-associated protein 1