BRD-K87909389_alvocidib_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K87909389_alvocidib_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY9 adenylate cyclase 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ETV1 ets variant 1
FBN2 fibrillin 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXC10 homeobox C10
IGHD immunoglobulin heavy constant delta
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MTSS1 metastasis suppressor 1
PRKCA protein kinase C, alpha
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TPD52 tumor protein D52
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
BAMBI BMP and activin membrane-bound inhibitor
CANT1 calcium activated nucleotidase 1
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNOT4 CCR4-NOT transcription complex, subunit 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOS FBJ murine osteosarcoma viral oncogene homolog
FZD7 frizzled class receptor 7
HMOX1 heme oxygenase 1
IER2 immediate early response 2
IER3 immediate early response 3
IER5 immediate early response 5
KLF4 Kruppel-like factor 4 (gut)
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
RPS4Y1 ribosomal protein S4, Y-linked 1
SOX9 SRY (sex determining region Y)-box 9
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZFP36L1 ZFP36 ring finger protein-like 1