BRD-K87909389_alvocidib_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K87909389_alvocidib_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ALCAM activated leukocyte cell adhesion molecule
ANXA6 annexin A6
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCND2 cyclin D2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
FAM171A1 family with sequence similarity 171, member A1
FOLR1 folate receptor 1 (adult)
GAB2 GRB2-associated binding protein 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
NEFH neurofilament, heavy polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
PRDX2 peroxiredoxin 2
TBC1D4 TBC1 domain family, member 4
TFF1 trefoil factor 1
TMEM110 transmembrane protein 110
TSPAN8 tetraspanin 8
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL4C ADP-ribosylation factor-like 4C
CALML5 calmodulin-like 5
CCNE2 cyclin E2
CCNF cyclin F
CD24 CD24 molecule
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF5 eukaryotic translation initiation factor 5
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IGFBP6 insulin-like growth factor binding protein 6
IGKV1-5 immunoglobulin kappa variable 1-5
JUN jun proto-oncogene
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT6B keratin 6B, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEF2C myocyte enhancer factor 2C
NFE2L2 nuclear factor, erythroid 2-like 2
NRIP1 nuclear receptor interacting protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PMM2 phosphomannomutase 2
PPAP2B phosphatidic acid phosphatase type 2B
S100A7 S100 calcium binding protein A7
SDC4 syndecan 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SMAD7 SMAD family member 7
SOX9 SRY (sex determining region Y)-box 9
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
XBP1 X-box binding protein 1
ZFP36 ZFP36 ring finger protein