BRD-K87737963_CYT387_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

73 genes differentially expressed following the BRD-K87737963_CYT387_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK AHNAK nucleoprotein
AHR aryl hydrocarbon receptor
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BHLHE40 basic helix-loop-helix family, member e40
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFD complement factor D (adipsin)
CLDN10 claudin 10
CPE carboxypeptidase E
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSTA cystatin A (stefin A)
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMXL2 Dmx-like 2
DOK5 docking protein 5
FAS Fas cell surface death receptor
FLNA filamin A, alpha
HAL histidine ammonia-lyase
KIF5C kinesin family member 5C
KLF10 Kruppel-like factor 10
KRT19 keratin 19, type I
NR2F2 nuclear receptor subfamily 2, group F, member 2
OXA1L oxidase (cytochrome c) assembly 1-like
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RNASET2 ribonuclease T2
S100A10 S100 calcium binding protein A10
SDC4 syndecan 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPATS2L spermatogenesis associated, serine-rich 2-like
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha
TLR4 toll-like receptor 4
TPD52 tumor protein D52
TSPAN4 tetraspanin 4
VCAN versican
ZNF512B zinc finger protein 512B

decreased expression

Symbol Name
APOD apolipoprotein D
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CDKN2A cyclin-dependent kinase inhibitor 2A
CNN3 calponin 3, acidic
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
EPHB2 EPH receptor B2
GADD45B growth arrest and DNA-damage-inducible, beta
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HLA-C major histocompatibility complex, class I, C
HP haptoglobin
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
ITM2A integral membrane protein 2A
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LYN LYN proto-oncogene, Src family tyrosine kinase
MCOLN1 mucolipin 1
MDK midkine (neurite growth-promoting factor 2)
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RGCC regulator of cell cycle
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPON2 spondin 2, extracellular matrix protein
SPP1 secreted phosphoprotein 1
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
VAV3 vav 3 guanine nucleotide exchange factor