BRD-K87737963_CYT387_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K87737963_CYT387_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT7 acyl-CoA thioesterase 7
ADO 2-aminoethanethiol (cysteamine) dioxygenase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL4A6 collagen, type IV, alpha 6
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEGS1 delta(4)-desaturase, sphingolipid 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYD dihydropyrimidine dehydrogenase
DUSP7 dual specificity phosphatase 7
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
HNMT histamine N-methyltransferase
HOPX HOP homeobox
HOXC6 homeobox C6
IL7R interleukin 7 receptor
KCTD12 potassium channel tetramerization domain containing 12
KRT17 keratin 17, type I
LEPROTL1 leptin receptor overlapping transcript-like 1
LPAR1 lysophosphatidic acid receptor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MMP7 matrix metallopeptidase 7
MSMO1 methylsterol monooxygenase 1
NPY1R neuropeptide Y receptor Y1
PI3 peptidase inhibitor 3, skin-derived
PLAT plasminogen activator, tissue
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THAP11 THAP domain containing 11
TLE4 transducin-like enhancer of split 4
TM4SF1 transmembrane 4 L six family member 1
TOX3 TOX high mobility group box family member 3
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
AEBP1 AE binding protein 1
AKR1C3 aldo-keto reductase family 1, member C3
ANGPTL2 angiopoietin-like 2
ASRGL1 asparaginase like 1
CFD complement factor D (adipsin)
CKB creatine kinase, brain
CTGF connective tissue growth factor
DNTT DNA nucleotidylexotransferase
EMX2 empty spiracles homeobox 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
HEBP2 heme binding protein 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KIF5C kinesin family member 5C
LOC100505650 uncharacterized LOC100505650
MAP7 microtubule-associated protein 7
MID1 midline 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1M metallothionein 1M
NEBL nebulette
OLFML3 olfactomedin-like 3
PCP4 Purkinje cell protein 4
PDLIM1 PDZ and LIM domain 1
PLIN2 perilipin 2
PROM1 prominin 1
RGCC regulator of cell cycle
SASH1 SAM and SH3 domain containing 1
SCGB2A1 secretoglobin, family 2A, member 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM243 transmembrane protein 243, mitochondrial
TPD52L1 tumor protein D52-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1
ZHX2 zinc fingers and homeoboxes 2