BRD-K87737963_CYT387_HS578T_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K87737963_CYT387_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADD3 adducin 3 (gamma)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANGPT1 angiopoietin 1
BST2 bone marrow stromal cell antigen 2
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD164 CD164 molecule, sialomucin
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN10 claudin 10
CYB561 cytochrome b561
EFNB2 ephrin-B2
EVI2A ecotropic viral integration site 2A
FLRT2 fibronectin leucine rich transmembrane protein 2
FLT1 fms-related tyrosine kinase 1
GATA3 GATA binding protein 3
HOPX HOP homeobox
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LIMCH1 LIM and calponin homology domains 1
LPAR1 lysophosphatidic acid receptor 1
LPAR6 lysophosphatidic acid receptor 6
LPIN1 lipin 1
NRP1 neuropilin 1
OLFML2A olfactomedin-like 2A
PBX1 pre-B-cell leukemia homeobox 1
PEG10 paternally expressed 10
PEX11A peroxisomal biogenesis factor 11 alpha
PNMA2 paraneoplastic Ma antigen 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRM protein tyrosine phosphatase, receptor type, M
SDC1 syndecan 1
SESN1 sestrin 1
SLIT3 slit homolog 3 (Drosophila)
SMAD3 SMAD family member 3
SPATA20 spermatogenesis associated 20
SST somatostatin
TBX3 T-box 3
THY1 Thy-1 cell surface antigen
TTC3 tetratricopeptide repeat domain 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VNN1 vanin 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZNF395 zinc finger protein 395
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AEBP1 AE binding protein 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BEX1 brain expressed, X-linked 1
CCL2 chemokine (C-C motif) ligand 2
CCNE2 cyclin E2
CENPU centromere protein U
CHN2 chimerin 2
CLDN3 claudin 3
COBL cordon-bleu WH2 repeat protein
COCH cochlin
CTPS1 CTP synthase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GADD45B growth arrest and DNA-damage-inducible, beta
HMGB2 high mobility group box 2
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IER3 immediate early response 3
IGF1R insulin-like growth factor 1 receptor
IL6 interleukin 6
MAP7 microtubule-associated protein 7
MMP7 matrix metallopeptidase 7
NKX3-1 NK3 homeobox 1
PCNA proliferating cell nuclear antigen
PDLIM3 PDZ and LIM domain 3
PDLIM5 PDZ and LIM domain 5
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RCAN1 regulator of calcineurin 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SFRP1 secreted frizzled-related protein 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPP1 secreted phosphoprotein 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TF transferrin
USP6NL USP6 N-terminal like