BRD-K87737963_CYT387_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K87737963_CYT387_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
APOD apolipoprotein D
ESR1 estrogen receptor 1
MFAP5 microfibrillar associated protein 5
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

decreased expression

Symbol Name
BGN biglycan
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSRP2 cysteine and glycine-rich protein 2
CYB5A cytochrome b5 type A (microsomal)
FST follistatin
GNLY granulysin
GOLT1B golgi transport 1B
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)
HSPA2 heat shock 70kDa protein 2
IL7R interleukin 7 receptor
INSIG1 insulin induced gene 1
LCK LCK proto-oncogene, Src family tyrosine kinase
NT5DC2 5'-nucleotidase domain containing 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
S100A9 S100 calcium binding protein A9
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SGK1 serum/glucocorticoid regulated kinase 1
TFPI2 tissue factor pathway inhibitor 2
TLR4 toll-like receptor 4
VCAM1 vascular cell adhesion molecule 1
ZHX2 zinc fingers and homeoboxes 2