BRD-K87387614_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K87387614_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
ARMCX2 armadillo repeat containing, X-linked 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD163 CD163 molecule
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRDL1 chordin-like 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FCGBP Fc fragment of IgG binding protein
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
GLRX glutaredoxin (thioltransferase)
HMOX1 heme oxygenase 1
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IGFBP6 insulin-like growth factor binding protein 6
KRT19 keratin 19, type I
LGALS1 lectin, galactoside-binding, soluble, 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MT1F metallothionein 1F
MT1X metallothionein 1X
MVP major vault protein
NES nestin
NPTX2 neuronal pentraxin II
NRCAM neuronal cell adhesion molecule
NUPR1 nuclear protein, transcriptional regulator, 1
OSBPL10 oxysterol binding protein-like 10
PAM peptidylglycine alpha-amidating monooxygenase
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PERP PERP, TP53 apoptosis effector
PIR pirin (iron-binding nuclear protein)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRAF2 PRA1 domain family, member 2
PYCARD PYD and CARD domain containing
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A1 secretoglobin, family 2A, member 1
SELENBP1 selenium binding protein 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SYT1 synaptotagmin I
TMSB15A thymosin beta 15a
TNNT1 troponin T type 1 (skeletal, slow)
TSKU tsukushi, small leucine rich proteoglycan
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VSIG4 V-set and immunoglobulin domain containing 4
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
BOP1 block of proliferation 1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CXCL13 chemokine (C-X-C motif) ligand 13
DBF4 DBF4 zinc finger
DPH2 DPH2 homolog (S. cerevisiae)
LIG1 ligase I, DNA, ATP-dependent
MRPS2 mitochondrial ribosomal protein S2
MSMB microseminoprotein, beta-
PAEP progestagen-associated endometrial protein
PPIF peptidylprolyl isomerase F
PRPF4 pre-mRNA processing factor 4
PURA purine-rich element binding protein A
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
WT1 Wilms tumor 1