BRD-K87158025_-666_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-K87158025_-666_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
C1ORF106 chromosome 1 open reading frame 106
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
COL15A1 collagen, type XV, alpha 1
COL4A5 collagen, type IV, alpha 5
DLK1 delta-like 1 homolog (Drosophila)
DSTN destrin (actin depolymerizing factor)
FBN2 fibrillin 2
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOMER3 homer scaffolding protein 3
ICAM1 intercellular adhesion molecule 1
KDM5D lysine (K)-specific demethylase 5D
LMNA lamin A/C
MMP13 matrix metallopeptidase 13
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MUC16 mucin 16, cell surface associated
NR1H2 nuclear receptor subfamily 1, group H, member 2
PRAME preferentially expressed antigen in melanoma
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SPON2 spondin 2, extracellular matrix protein
TGFA transforming growth factor, alpha
TPSAB1 tryptase alpha/beta 1
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADD3 adducin 3 (gamma)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALCAM activated leukocyte cell adhesion molecule
ARMCX2 armadillo repeat containing, X-linked 2
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK4 cyclin-dependent kinase 4
CLU clusterin
CRYAB crystallin, alpha B
CSTA cystatin A (stefin A)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CYCS cytochrome c, somatic
CYFIP2 cytoplasmic FMR1 interacting protein 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
EDNRB endothelin receptor type B
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
FZD7 frizzled class receptor 7
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
HACD2 3-hydroxyacyl-CoA dehydratase 2
HBB hemoglobin, beta
IGHM immunoglobulin heavy constant mu
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LEPR leptin receptor
LUM lumican
LXN latexin
LY96 lymphocyte antigen 96
MARCKS myristoylated alanine-rich protein kinase C substrate
MSX1 msh homeobox 1
NRIP1 nuclear receptor interacting protein 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PEG10 paternally expressed 10
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PPA1 pyrophosphatase (inorganic) 1
PSPH phosphoserine phosphatase
PTGES prostaglandin E synthase
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS4 regulator of G-protein signaling 4
S100A13 S100 calcium binding protein A13
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SNAI2 snail family zinc finger 2
SOX9 SRY (sex determining region Y)-box 9
SRGN serglycin
STAT1 signal transducer and activator of transcription 1, 91kDa
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM176B transmembrane protein 176B
USP22 ubiquitin specific peptidase 22
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBTB38 zinc finger and BTB domain containing 38