BRD-K87142802_veliparib_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K87142802_veliparib_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACP5 acid phosphatase 5, tartrate resistant
ANPEP alanyl (membrane) aminopeptidase
AQP3 aquaporin 3 (Gill blood group)
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC42 cell division cycle 42
COG7 component of oligomeric golgi complex 7
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
CPVL carboxypeptidase, vitellogenic-like
CRYAB crystallin, alpha B
EGR1 early growth response 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FOS FBJ murine osteosarcoma viral oncogene homolog
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
KRT19 keratin 19, type I
MAP2K5 mitogen-activated protein kinase kinase 5
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
NPY1R neuropeptide Y receptor Y1
PAN2 PAN2 poly(A) specific ribonuclease subunit
POSTN periostin, osteoblast specific factor
SCN3A sodium channel, voltage gated, type III alpha subunit
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPARCL1 SPARC-like 1 (hevin)
SPON2 spondin 2, extracellular matrix protein
SRSF6 serine/arginine-rich splicing factor 6
STC1 stanniocalcin 1

decreased expression

Symbol Name
ADAM9 ADAM metallopeptidase domain 9
AGR2 anterior gradient 2
AHCYL1 adenosylhomocysteinase-like 1
BTG3 BTG family, member 3
CCL20 chemokine (C-C motif) ligand 20
CD36 CD36 molecule (thrombospondin receptor)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
COL15A1 collagen, type XV, alpha 1
DEFB1 defensin, beta 1
FAM13A family with sequence similarity 13, member A
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
HOXB6 homeobox B6
LDLR low density lipoprotein receptor
LIMCH1 LIM and calponin homology domains 1
MAGEA6 melanoma antigen family A6
MAP1B microtubule-associated protein 1B
MMD monocyte to macrophage differentiation-associated
NQO1 NAD(P)H dehydrogenase, quinone 1
PBX1 pre-B-cell leukemia homeobox 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEX11A peroxisomal biogenesis factor 11 alpha
PLCB4 phospholipase C, beta 4
PON2 paraoxonase 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3
TOB1 transducer of ERBB2, 1
TPD52L1 tumor protein D52-like 1
TXNL4B thioredoxin-like 4B