BRD-K87142802_veliparib_HEPG2_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K87142802_veliparib_HEPG2_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG1 arginase 1
BACE2 beta-site APP-cleaving enzyme 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFI complement factor I
COCH cochlin
CP ceruloplasmin (ferroxidase)
CRABP1 cellular retinoic acid binding protein 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DSG3 desmoglein 3
EREG epiregulin
FPR1 formyl peptide receptor 1
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MAP1B microtubule-associated protein 1B
MMP10 matrix metallopeptidase 10
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NKX3-1 NK3 homeobox 1
NNMT nicotinamide N-methyltransferase
NPTX2 neuronal pentraxin II
NSG1 neuron specific gene family member 1
OLFM1 olfactomedin 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
SCGB2A2 secretoglobin, family 2A, member 2
TFPI2 tissue factor pathway inhibitor 2
TGM2 transglutaminase 2
TM6SF1 transmembrane 6 superfamily member 1
TNNT1 troponin T type 1 (skeletal, slow)
TPM4 tropomyosin 4
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
COL9A3 collagen, type IX, alpha 3
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
GPC3 glypican 3
GPM6A glycoprotein M6A
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KRT18 keratin 18, type I
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS1 lectin, galactoside-binding, soluble, 1
LITAF lipopolysaccharide-induced TNF factor
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MECOM MDS1 and EVI1 complex locus
MEIS1 Meis homeobox 1
MGP matrix Gla protein
MXRA5 matrix-remodelling associated 5
NRIP1 nuclear receptor interacting protein 1
OAT ornithine aminotransferase
PRDX2 peroxiredoxin 2
RCAN2 regulator of calcineurin 2
SFRP1 secreted frizzled-related protein 1
SPRED2 sprouty-related, EVH1 domain containing 2
STC1 stanniocalcin 1
TCF4 transcription factor 4
TLR4 toll-like receptor 4
TNIP1 TNFAIP3 interacting protein 1
TRIM2 tripartite motif containing 2
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)