BRD-K87142802_veliparib_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K87142802_veliparib_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BST2 bone marrow stromal cell antigen 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CRABP2 cellular retinoic acid binding protein 2
DEGS1 delta(4)-desaturase, sphingolipid 1
DST dystonin
EPCAM epithelial cell adhesion molecule
FBN1 fibrillin 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KLK8 kallikrein-related peptidase 8
KRT14 keratin 14, type I
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYZ lysozyme
METTL7A methyltransferase like 7A
PIP prolactin-induced protein
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAD23B RAD23 homolog B (S. cerevisiae)
RGCC regulator of cell cycle
RPS4Y1 ribosomal protein S4, Y-linked 1
RTN1 reticulon 1
SPON2 spondin 2, extracellular matrix protein
STK10 serine/threonine kinase 10
TACSTD2 tumor-associated calcium signal transducer 2
TCTA T-cell leukemia translocation altered
TM9SF3 transmembrane 9 superfamily member 3
TPD52 tumor protein D52
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANXA5 annexin A5
APP amyloid beta (A4) precursor protein
CAV1 caveolin 1, caveolae protein, 22kDa
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CKB creatine kinase, brain
CLU clusterin
DLC1 DLC1 Rho GTPase activating protein
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EREG epiregulin
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP1 fatty acid binding protein 1, liver
FHL1 four and a half LIM domains 1
GNLY granulysin
GPI glucose-6-phosphate isomerase
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
KIAA0226L KIAA0226-like
LEFTY1 left-right determination factor 1
LOC100505650 uncharacterized LOC100505650
MYO5C myosin VC
OLFM4 olfactomedin 4
PDE4B phosphodiesterase 4B, cAMP-specific
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGAM1 phosphoglycerate mutase 1 (brain)
PKM pyruvate kinase, muscle
PPAP2B phosphatidic acid phosphatase type 2B
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SEPP1 selenoprotein P, plasma, 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBCB tubulin folding cofactor B
TMEM47 transmembrane protein 47
TPM4 tropomyosin 4
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRAF5 TNF receptor-associated factor 5
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon