BRD-K87142802_veliparib_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K87142802_veliparib_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACD adrenocortical dysplasia homolog (mouse)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKRD36B ankyrin repeat domain 36B
ASRGL1 asparaginase like 1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALR calreticulin
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC2B C-type lectin domain family 2, member B
CORO1A coronin, actin binding protein, 1A
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DUSP6 dual specificity phosphatase 6
FKBP1A FK506 binding protein 1A, 12kDa
HSPA2 heat shock 70kDa protein 2
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
JCHAIN joining chain of multimeric IgA and IgM
LAPTM5 lysosomal protein transmembrane 5
LCN2 lipocalin 2
LTB lymphotoxin beta (TNF superfamily, member 3)
MARCKS myristoylated alanine-rich protein kinase C substrate
MMP9 matrix metallopeptidase 9
NGRN neugrin, neurite outgrowth associated
ORM1 orosomucoid 1
PAEP progestagen-associated endometrial protein
PLIN2 perilipin 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TM9SF3 transmembrane 9 superfamily member 3
ZIC1 Zic family member 1

decreased expression

Symbol Name
ACTB actin, beta
ANXA3 annexin A3
CAST calpastatin
CCDC92 coiled-coil domain containing 92
CDC42 cell division cycle 42
CRYAB crystallin, alpha B
CSRP1 cysteine and glycine-rich protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EIF5A eukaryotic translation initiation factor 5A
HBEGF heparin-binding EGF-like growth factor
NR1H2 nuclear receptor subfamily 1, group H, member 2
PDGFC platelet derived growth factor C
REEP5 receptor accessory protein 5
RHOQ ras homolog family member Q
RNH1 ribonuclease/angiogenin inhibitor 1
RPS11 ribosomal protein S11
S100A10 S100 calcium binding protein A10
SLC16A4 solute carrier family 16, member 4
TBX2 T-box 2
TPD52L1 tumor protein D52-like 1
WDR7 WD repeat domain 7