BRD-K86930074_S1017_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-K86930074_S1017_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
AQP1 aquaporin 1 (Colton blood group)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BLNK B-cell linker
BTG2 BTG family, member 2
CCND2 cyclin D2
CD24 CD24 molecule
CD9 CD9 molecule
CDH13 cadherin 13
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP4 cytoskeleton-associated protein 4
CLCA4 chloride channel accessory 4
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRISP3 cysteine-rich secretory protein 3
DHDDS dehydrodolichyl diphosphate synthase
DPYSL3 dihydropyrimidinase-like 3
ECM1 extracellular matrix protein 1
EFNA1 ephrin-A1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FILIP1L filamin A interacting protein 1-like
FN1 fibronectin 1
FRY furry homolog (Drosophila)
GREM1 gremlin 1, DAN family BMP antagonist
HIST2H2BE histone cluster 2, H2be
INSM1 insulinoma-associated 1
IPO13 importin 13
KRT18 keratin 18, type I
LAPTM5 lysosomal protein transmembrane 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MVP major vault protein
MYO1D myosin ID
NSDHL NAD(P) dependent steroid dehydrogenase-like
NXN nucleoredoxin
OBSL1 obscurin-like 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
PAWR PRKC, apoptosis, WT1, regulator
PELI1 pellino E3 ubiquitin protein ligase 1
PTPRE protein tyrosine phosphatase, receptor type, E
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RBPMS RNA binding protein with multiple splicing
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SNX7 sorting nexin 7
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST18 suppression of tumorigenicity 18, zinc finger
STON1 stonin 1
SULF1 sulfatase 1
TPSAB1 tryptase alpha/beta 1
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP8 vesicle-associated membrane protein 8
VWF von Willebrand factor
WIPI1 WD repeat domain, phosphoinositide interacting 1
XIST X inactive specific transcript (non-protein coding)
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATF1 activating transcription factor 1
CDC20 cell division cycle 20
CDC42 cell division cycle 42
CDK6 cyclin-dependent kinase 6
CLINT1 clathrin interactor 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTSH cathepsin H
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF4E eukaryotic translation initiation factor 4E
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GCH1 GTP cyclohydrolase 1
HMGA1 high mobility group AT-hook 1
HNRNPL heterogeneous nuclear ribonucleoprotein L
IFI6 interferon, alpha-inducible protein 6
IFRD2 interferon-related developmental regulator 2
KDM5D lysine (K)-specific demethylase 5D
KRT10 keratin 10, type I
KYNU kynureninase
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MARCKS myristoylated alanine-rich protein kinase C substrate
NBN nibrin
NCK1 NCK adaptor protein 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPY neuropeptide Y
NUTF2 nuclear transport factor 2
PAK1IP1 PAK1 interacting protein 1
PMP22 peripheral myelin protein 22
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTDSS1 phosphatidylserine synthase 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RGS4 regulator of G-protein signaling 4
RPP25 ribonuclease P/MRP 25kDa subunit
RYK receptor-like tyrosine kinase
SCML1 sex comb on midleg-like 1 (Drosophila)
SET SET nuclear proto-oncogene
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLIRP SRA stem-loop interacting RNA binding protein
SMAD3 SMAD family member 3
SRSF1 serine/arginine-rich splicing factor 1
TMPO thymopoietin
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPYL5 TSPY-like 5
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
WDR12 WD repeat domain 12
WWTR1 WW domain containing transcription regulator 1