BRD-K86797399_pracinostat_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K86797399_pracinostat_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALDOC aldolase C, fructose-bisphosphate
ANO10 anoctamin 10
C8ORF4 chromosome 8 open reading frame 4
CD36 CD36 molecule (thrombospondin receptor)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CPT1A carnitine palmitoyltransferase 1A (liver)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DLD dihydrolipoamide dehydrogenase
DOCK9 dedicator of cytokinesis 9
DPYSL2 dihydropyrimidinase-like 2
EGLN3 egl-9 family hypoxia-inducible factor 3
FZD7 frizzled class receptor 7
HBB hemoglobin, beta
ISG15 ISG15 ubiquitin-like modifier
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LACTB2 lactamase, beta 2
LIPA lipase A, lysosomal acid, cholesterol esterase
MAP7 microtubule-associated protein 7
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PCDH9 protocadherin 9
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDZK1 PDZ domain containing 1
PRAF2 PRA1 domain family, member 2
QPCT glutaminyl-peptide cyclotransferase
RCAN1 regulator of calcineurin 1
RGS1 regulator of G-protein signaling 1
S100P S100 calcium binding protein P
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STC1 stanniocalcin 1
SYT1 synaptotagmin I
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB2 tribbles pseudokinase 2
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5
TXNRD1 thioredoxin reductase 1
TYROBP TYRO protein tyrosine kinase binding protein
WRB tryptophan rich basic protein

decreased expression

Symbol Name
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CCNB2 cyclin B2
CFH complement factor H
CKS1B CDC28 protein kinase regulatory subunit 1B
CLU clusterin
COCH cochlin
DCK deoxycytidine kinase
DCN decorin
DPYD dihydropyrimidine dehydrogenase
EIF5 eukaryotic translation initiation factor 5
FEN1 flap structure-specific endonuclease 1
FOSL1 FOS-like antigen 1
GSAP gamma-secretase activating protein
GUSBP11 glucuronidase, beta pseudogene 11
HACD3 3-hydroxyacyl-CoA dehydratase 3
HMGB2 high mobility group box 2
HTRA1 HtrA serine peptidase 1
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
JCHAIN joining chain of multimeric IgA and IgM
KCTD12 potassium channel tetramerization domain containing 12
KIAA0101 KIAA0101
KLK11 kallikrein-related peptidase 11
LMNB1 lamin B1
LOC100505650 uncharacterized LOC100505650
LTF lactotransferrin
MCM2 minichromosome maintenance complex component 2
MUC1 mucin 1, cell surface associated
NID1 nidogen 1
PCNA proliferating cell nuclear antigen
PIP prolactin-induced protein
PLS3 plastin 3
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SMC4 structural maintenance of chromosomes 4
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNX7 sorting nexin 7
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARCL1 SPARC-like 1 (hevin)
SPRR3 small proline-rich protein 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCL1A T-cell leukemia/lymphoma 1A
TFPI2 tissue factor pathway inhibitor 2
TGFBR3 transforming growth factor, beta receptor III
TOP2A topoisomerase (DNA) II alpha 170kDa
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XBP1 X-box binding protein 1