BRD-K86797399_pracinostat_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K86797399_pracinostat_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
AQP3 aquaporin 3 (Gill blood group)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EFNA1 ephrin-A1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXO4 forkhead box O4
GPRC5A G protein-coupled receptor, class C, group 5, member A
IFI6 interferon, alpha-inducible protein 6
IGF2R insulin-like growth factor 2 receptor
IGFBP5 insulin-like growth factor binding protein 5
L1CAM L1 cell adhesion molecule
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MATN2 matrilin 2
MT1X metallothionein 1X
MT2A metallothionein 2A
NEFL neurofilament, light polypeptide
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK1 proprotein convertase subtilisin/kexin type 1
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SGCE sarcoglycan, epsilon
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS1 thrombospondin 1
TNNT1 troponin T type 1 (skeletal, slow)
UBE2L6 ubiquitin-conjugating enzyme E2L 6

decreased expression

Symbol Name
AEBP1 AE binding protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
GREM1 gremlin 1, DAN family BMP antagonist
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT5 keratin 5, type II
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
ODC1 ornithine decarboxylase 1
PHF11 PHD finger protein 11
PRAME preferentially expressed antigen in melanoma
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RCC1 regulator of chromosome condensation 1
RGCC regulator of cell cycle
RSL1D1 ribosomal L1 domain containing 1
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
TWIST1 twist family bHLH transcription factor 1